Dr. John DeSpain offers a full array of medical, surgical and cosmetic dermatology services. He provides expert cares for skin condition such as psoriasis, eczema, acne, rosacea, skin cancer, and moles. Dr. DeSpain enjoys caring for patients of all ages.

About John DeSpain, M.D.

Dr. DeSpain is a member of the American Academy of Dermatology and the Missouri Dermatologic Society.

After medical school at the University of Missouri, he trained in Denver and then returned to serve full-time on the faculty at the University for several years before starting private practice in 1992. His practice has evolved to offer a full range of medical, surgical, and cosmetic dermatology services.

In his spare time he enjoys time with his family, flyfishing, golf, boating, exercising, cooking, and cycling. He enjoys cooking and tasting wines and traveling with his wife Darla, who is an accomplished Family Nurse Practitioner. He has two grown daughters and three grown stepsons, as well as two stepsons at home.


Dr. John DeSpain attained his undergraduate and medical degrees, and completed his dermatology residency at The University of Missouri, Columbia. He also interned in Denver and completed his fellowship in Dermatopathology.


Dr. DeSpain currently holds board certification in both Dermatology and Dermatopathology.