Last updated: August 17, 2021

On Friday, August 13, 2021, the CDC recommended that patients with moderate to severe immunosuppression who have received a Pfizer or Moderna COVID vaccine should receive a third (“booster”) vaccination.

What to Know About Booster Doses

Only patients with moderate to severe immunosuppression are currently qualified to receive the booster.

Examples of “moderate to severe immunosuppression” include: Asplenia, Cancer (Solid Tumor and Hematologic Malignancies), Chronic Renal Disease, HIV, and Organ/Bone Marrow Transplant, along with patients who are taking immune-suppressive medications for autoimmune conditions such as Colitis, Lupus, Multiple Sclerosis, Psoriasis, and Rheumatoid Arthritis. It’s estimated that 2.7% of US adults are immunocompromised patients.

Additional Facts About a Booster Dose:

  • Chronic disease conditions (such as diabetes and hypertension) are not clinical indications for receiving a booster dose; patients are encouraged to speak with their Primary Care Provider if they have any questions about qualifying for a booster dose.
  • As existing clinical data is insufficient, there are no current recommendations on a booster dose for patients who have received a Johnson & Johnson vaccine.
  • Patients must be at least 28 days from administration of the second vaccine to receive the booster dose.
  • It’s recommended to receive the same manufacturer as the initial vaccine series.

How Can You Receive a Booster?

Qualifying patients can receive a booster vaccine by walking in at the COVID Vaccine Clinic, calling (573) 556-7745, or booking online here.


The COVID Immunization Clinic is open most Mondays through Fridays 8:30 a.m. to 4:00 p.m., located on the second floor of 1241 W Stadium Blvd.


You can sign up for an appointment by calling our COVID Clinic at (573) 556-7745.

Signing Up – Online

Go to and follow the instructions.

What Else Should I Know?

  • Patients with compromised immune systems may still be at risk for COVID-19, even with the additional vaccine dose. They should continue to take precautions, including wearing masks, avoiding crowded, indoor, poorly ventilated places that are higher risk for spreading COVID-19, and practicing good hand hygiene.
  • Vaccine supply at JCMG remains strong and we are well prepared to administer booster doses to our patients.